Safety and immune regulatory properties of canine induced pluripotent stem cell-derived mesenchymal stem cells

Mesenchymal stem cells (MSCs) exhibit broad immune modulatory activity in vivo and can suppress T cell proliferation and dendritic cell activation in vitro. Currently, most MSC for clinical usage are derived from younger donors, due to ease of procurement and to the superior immune modulatory activi...

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Hauptverfasser: Lyndah Chow, Valerie Johnson, Dan Regan, William Wheat, Saiphone Webb, Peter Koch, Steven Dow
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017-12-01
Schriftenreihe:Stem Cell Research
Schlagworte:
Dog
Immune
Teratoma
T cell
Online Zugang:http://www.sciencedirect.com/science/article/pii/S1873506117302404
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