Tart Cherry Increases Lifespan in <i>Caenorhabditis elegans</i> by Altering Metabolic Signaling Pathways

Aging and healthspan are determined by both environmental and genetic factors. The insulin/insulin-like growth factor-1(IGF-1) pathway is a key mediator of aging in <i>Caenorhabditis elegans</i> and mammals. Specifically, DAF-2 signaling, an ortholog of human IGF, controls DAF-16/FOXO tr...

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Detalhes bibliográficos
Main Authors: Shasika Jayarathne, Latha Ramalingam, Hunter Edwards, Siva A. Vanapalli, Naima Moustaid-Moussa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-05-01
Colecção:Nutrients
Assuntos:
<i>C. elegans</i>
tart cherry
lifespan
aging
oxidative stress
<i>daf-16</i>
Acesso em linha:https://www.mdpi.com/2072-6643/12/5/1482
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