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Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19
Abstract Background Natural killer (NK) cells are innate lymphoid cells that mediate antitumour and antiviral responses. However, very little is known about how ageing influences human NK cells, especially at the single-cell level. Methods We applied single-cell sequencing (scRNA-seq) to human lymph...
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Główni autorzy: | , , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
BMC
2022-05-01
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Seria: | Genome Medicine |
Hasła przedmiotowe: | |
Dostęp online: | https://doi.org/10.1186/s13073-022-01049-3 |
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