Pharmacokinetic and metabolomic analyses of Mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease

Abstract Background Non-alcoholic fatty liver is one of the most common comorbidities of diabetes. It can cause disturbance of glucose and lipid metabolism in the body, gradually develop into liver fibrosis, and even cause liver cirrhosis. Mangiferin has a variety of pharmacological activities, espe...

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Hauptverfasser: He Lin, Houlei Teng, Wei Wu, Yong Li, Guangfu Lv, Xiaowei Huang, Wenhao Yan, Zhe Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-08-01
Schriftenreihe:BMC Pharmacology and Toxicology
Schlagworte:
Mangiferin calcium salt
Diabetes
NAFLD
Pharmacokinetics
Metabolomics
Bioavailability
Online Zugang:http://link.springer.com/article/10.1186/s40360-020-00438-x
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