Increased atherosclerosis in a mouse model of glycogen storage disease type 1a

Glycogen storage disease type 1a (GSD Ia) is an inborn error of carbohydrate metabolism. Despite severe hyperlipidemia, GSD Ia patients show limited atherogenesis compared to age-and-gender matched controls. Employing a GSD Ia mouse model that resembles the severe hyperlipidemia in patients, we here...

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Autores principales: Anouk M. La Rose, Anouk G. Groenen, Benedek Halmos, Venetia Bazioti, Martijn G.S. Rutten, Kishore A. Krishnamurthy, Mirjam H. Koster, Niels J. Kloosterhuis, Marieke Smit, Rick Havinga, Gilles Mithieux, Fabienne Rajas, Folkert Kuipers, Maaike H. Oosterveer, Marit Westerterp
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2022-06-01
Colección:Molecular Genetics and Metabolism Reports
Materias:
Glycogen storage disease type 1a
Atherosclerosis
Hyperlipidemia
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2214426922000325
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