Epigenetic Modification of CFTR in Head and Neck Cancer

Cystic fibrosis transmembrane conductance regulator (CFTR), a cyclic AMP (cAMP)-regulated chloride channel, is critical for secretion and absorption across diverse epithelia. Mutations or absence of CFTR result in pathogeneses, including cancer. While CFTR has been proposed as a tumor suppressing ge...

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Bibliografiset tiedot
Päätekijät: Yonghwan Shin, Minkyoung Kim, Jonghwa Won, Junchul Kim, Seog Bae Oh, Jong-Ho Lee, Kyungpyo Park
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2020-03-01
Sarja:Journal of Clinical Medicine
Aiheet:
cftr
head and neck cancer
5-aza-2′-deoxycytidine
epigenetic modification
dna methylation
hypermethylation
hypomethylation
Linkit:https://www.mdpi.com/2077-0383/9/3/734
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