Mycoplasma genitalium Protein of Adhesion Induces Inflammatory Cytokines via Cyclophilin A-CD147 Activating the ERK-NF-κB Pathway in Human Urothelial Cells

Mycoplasma genitalium protein of adhesion (MgPa) plays an important role in the process of adhesion and invasion of host cells by M. genitalium, and is thus significant for its pathogenic mechanisms in host cells. Our previous study has demonstrated that cyclophilin A (CypA) is the receptor for MgPa...

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Hlavní autoři: Lingling Li, Dan Luo, Yating Liao, Kailan Peng, Yanhua Zeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020-09-01
Edice:Frontiers in Immunology
Témata:
Mycoplasma genitalium
CD147
cyclophilin A
inflammatory cytokines
NF-κB
On-line přístup:https://www.frontiersin.org/article/10.3389/fimmu.2020.02052/full
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