Mycoplasma genitalium Protein of Adhesion Induces Inflammatory Cytokines via Cyclophilin A-CD147 Activating the ERK-NF-κB Pathway in Human Urothelial Cells

Mycoplasma genitalium protein of adhesion (MgPa) plays an important role in the process of adhesion and invasion of host cells by M. genitalium, and is thus significant for its pathogenic mechanisms in host cells. Our previous study has demonstrated that cyclophilin A (CypA) is the receptor for MgPa...

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Bibliographic Details
Main Authors: Lingling Li, Dan Luo, Yating Liao, Kailan Peng, Yanhua Zeng
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
Mycoplasma genitalium
CD147
cyclophilin A
inflammatory cytokines
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02052/full
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