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Bioactive Indanes: Proof of Concept Study for Enantioselective Synthetic Routes to PH46A, a New Potential Anti-Inflammatory Agent

PH46A is a single enantiomer and a member of the 1,2-indane dimer family. It has two contiguous stereogenic centers with S,S configurations, one of which being a quaternary center, which has been developed as a clinical candidate for the treatment of inflammatory and autoimmune conditions. The curre...

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Detalhes bibliográficos
Main Authors: Tao Zhang, Gaia Scalabrino, Neil Frankish, Helen Sheridan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-06-01
Colecção:Molecules
Assuntos:
Acesso em linha:http://www.mdpi.com/1420-3049/23/7/1503
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