Protective Role of Mast Cells in Primary Systemic Vasculitis: A Perspective

Mast cells are important cells of the immune system. Although traditionally considered as key players in allergic and hypersensitivity reactions, emerging evidence suggests that mast cells have many complex roles in vascular disease. These include regulation of vasodilation, angiogenesis, activation...

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Bibliographische Detailangaben
Hauptverfasser: Jason M. Springer, Vineesh V. Raveendran, Selina A. Gierer, Mehrdad Maz, Kottarappat N. Dileepan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017-08-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
mast cell
interleukin 6
suppressor of cytokine signaling-1
vasculitis
giant cell arteritis
aortitis
Online Zugang:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00990/full
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