Sequential allocation to balance prognostic factors in a psychiatric clinical trial

OBJECTIVE: This paper aims to describe and discuss a minimization procedure specifically designed for a clinical trial that evaluates treatment efficacy for OCD patients. METHOD: Aitchison's compositional distance was used to calculate vectors for each possibility of allocation in a covariate a...

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Bibliografski detalji
Glavni autori: Victor Fossaluza, Juliana Belo Diniz, Basilio de Bragança Pereira, Eurípedes Constantino Miguel, Carlos Alberto de Bragança Pereira
Format: Artigo
Jezik:Inglês
Izdano: Faculdade de Medicina / USP 2009-06-01
Serija:Clinics
Teme:
Clinical research
Randomization
Aitchison's compositional distance
Online pristup:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000600005
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