Intrinsic thermal sensing controls proteolysis of Yersinia virulence regulator RovA.

Pathogens, which alternate between environmental reservoirs and a mammalian host, frequently use thermal sensing devices to adjust virulence gene expression. Here, we identify the Yersinia virulence regulator RovA as a protein thermometer. Thermal shifts encountered upon host entry lead to a reversi...

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Autores principales: Katharina Herbst, Matthias Bujara, Ann Kathrin Heroven, Wiebke Opitz, Martin Weichert, Ariane Zimmermann, Petra Dersch
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2009-05-01
Colección:PLoS Pathogens
Acceso en línea:http://europepmc.org/articles/PMC2676509?pdf=render
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