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Restoration of ER proteostasis attenuates remote apoptotic cell death after spinal cord injury by reducing autophagosome overload

Abstract The pathogenic mechanisms that underlie the progression of remote degeneration after spinal cord injury (SCI) are not fully understood. In this study, we examined the relationship between endoplasmic reticulum (ER) stress and macroautophagy, hereafter autophagy, and its contribution to the...

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Detalhes bibliográficos
Main Authors: Elisa Bisicchia, Roberta Mastrantonio, Annalisa Nobili, Claudia Palazzo, Livia La Barbera, Laura Latini, Francesco Millozzi, Valeria Sasso, Daniela Palacios, Marcello D’Amelio, Maria Teresa Viscomi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2022-04-01
Colecção:Cell Death and Disease
Acesso em linha:https://doi.org/10.1038/s41419-022-04830-9
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