Anti-Inflammatory Potential of Newly Synthesized 4-[(Butylsulfinyl)methyl]-1,2-benzenediol in Lipopolysaccharide-Stimulated BV2 Microglia

In this study, we investigated the anti-inflammatory effects of newly synthesized 4-[(butylsulfinyl)methyl]-1,2-benzenediol (SMBD) in lipopolysaccharide (LPS)-stimulated BV2 microglia and the subsequent signaling events. Following stimulation with LPS, elevated production of nitric oxide (NO) and pr...

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Detalhes bibliográficos
Main Authors: Guk-Heui Jo, Il-Whan Choi, Jin-Woo Jeong, Gi-Young Kim, Jinwoo Kim, Hongsuk Suh, Chung-Ho Ryu, Wun-Jae Kim, Yung Hyun Choi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2014-10-01
Colecção:Molecules
Assuntos:
4-[(butylsulfinyl)methyl]-1,2-benzenediol
BV2 microglia
anti-inflammation
NF-κB
MAPKs
PI3K/Akt
Acesso em linha:http://www.mdpi.com/1420-3049/19/10/16609
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