Phenotypic and molecular states of IDH1 mutation-induced CD24-positive glioma stem-like cells

Mutations in IDH1 and IDH2 drive the development of gliomas. These genetic alterations promote tumor cell renewal, disrupt differentiation states, and induce stem-like properties. Understanding how this phenotypic reprogramming occurs remains an area of high interest in glioma research. Previously,...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Sara Haddock, Tyler J. Alban, Şevin Turcan, Hana Husic, Eric Rosiek, Xiaoxiao Ma, Yuxiang Wang, Tejus Bale, Alexis Desrichard, Vladimir Makarov, Sebastien Monette, Wei Wu, Rui Gardner, Katia Manova, Adrienne Boire, Timothy A. Chan
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2022-06-01
Серии:Neoplasia: An International Journal for Oncology Research
Предметы:
IDH1 mutation
Low-grade glioma
CD24
cancer stem cells
Neural stem cells
Orthotopic mouse model
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1476558622000197
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы