Discoidin domain receptor 1a (DDR1a) confers 5-fluorouracil cytotoxicity in LoVo cell via PI3K/AKT/Bcl-2 pathway

5-Fluorouracil (5-FU) is a common chemotherapy drug for patients with advanced colorectal cancer; however, many patients develop resistance to 5-FU and suffer from treatment failure. Discoidin domain receptor 1 (DDR1) is upregulated in multiple cancers and positively associated with chemoresistance....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bin Xiong, Fei-Xue Song, Hui-Ling Chen, Xiao-Juan Wang, Zheng-Xu Jin, Ti-Yun Han, Yi Li, De-Kui Zhang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis Group 2022-04-01
Cyfres:Bioengineered
Pynciau:
Discoidin domain receptor 1a
colorectal cancer
proliferation
cytotoxicity
5-fluorouracil
Mynediad Ar-lein:https://www.tandfonline.com/doi/10.1080/21655979.2022.2060782
Tagiau: Ychwanegu Tag
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