Altered Expression of Signaling Genes in Jurkat Cells upon FTY720 Induced Apoptosis

FTY720, a novel immunosuppressant, has a marked activity in decreasing peripheral blood T lymphocytes upon oral administration. Recent investigations suggest that the action of FTY720 on lymphocytes may result from its ability to induce cell apoptosis. However, the cell signaling mechanism involved...

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Main Authors: Shaoheng He, Xiaomin Zhu, Keqing Qian, Dunming Guo, Wenfeng Tan, Fang Wang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2010-09-01
Colecção:International Journal of Molecular Sciences
Assuntos:
FTY720
signal transduction
jurkat cell
apoptosis
cDNA microarray
Acesso em linha:http://www.mdpi.com/1422-0067/11/9/3087/
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