D-4F, an apolipoprotein A-I mimetic, promotes the clearance of myelin debris and the reduction of foamy macrophages after spinal cord injury

After spinal cord injury (SCI), a large number of blood-derived macrophages infiltrate the lesion site and phagocytose myelin debris to become foamy macrophages, which leads to chronic inflammation. The drug D-4F, an apolipoprotein A-I peptidomimetic made of D-amino acids, has been reported to promo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jinxin Li, Zhenyu Zhu, Yiteng Li, Yihao Chen, Xuyang Hu, Yanchang Liu, Yi Shi, Yao Hu, Yihui Bi, Xinzhong Xu, Meige Zheng, Li Cheng, Juehua Jing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis Group 2022-05-01
Cyfres:Bioengineered
Pynciau:
D-4F
spinal cord injury
foamy macrophages
myelin debris
ABCA1
Mynediad Ar-lein:https://www.tandfonline.com/doi/10.1080/21655979.2022.2073063
Tagiau: Ychwanegu Tag
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