Cortical neurogenesis in adult rats after ischemic brain injury: most new neurons fail to mature

The present study examines the hypothesis that endogenous neural progenitor cells isolated from the neocortex of ischemic brain can differentiate into neurons or glial cells and contribute to neural regeneration. We performed middle cerebral artery occlusion to establish a model of cerebral ischemia...

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Detalhes bibliográficos
Main Authors: Qing-quan Li, Guan-qun Qiao, Jun Ma, Hong-wei Fan, Ying-bin Li
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2015-01-01
Colecção:Neural Regeneration Research
Assuntos:
Alzheimer′s disease
amyloid-β
astrocytes
Ca 2+
calcilytic
calcium-sensing receptor
nitromemantine
NPS 2143
α7-nicotinic acetylcholine receptor
nerve regeneration
spinal cord injury
surgical decompression
tumor necrosis factor α
cell apoptosis
neurological function
neural regeneration
contusion
Nogo-A
axon growth
immunohistochemistry
fluorescent quantitative PCR
Schwann cells
cell transplantation
edaravone
motor function
electrophysiological function
electroacupuncture
intervertebral disc
blood circulation
inflammation
neuroprotection
neurons
NSFC grants
astrocytoma
mice
immunodeficiency (BALB/c) mice
Notch
nestin
glial fibrillary acidic protein
CD133
spinal cord
brain
MRI
earthquake
peripheral nerve injury
LSUHSC score
compartment syndrome
surgery therapy
physiotherapy
nerve decompression
brachial plexus injury
human amniotic epithelial cells
forepaw function
stress relaxation
creep
viscoelasticity
injection injury
cyclosporine A
penicillin G potassium
Wallerian degeneration
neuroelectrophysiology
Oenanthe javanica extract
cell proliferation
neuroblast differentiation
brain-derived neurotrophic factor
vascular endothelial growth factor
rat
middle cerebral artery occlusion
brain injury
oligodendrocytes
neural progenitor cells
proliferation
differentiation
neurogenesis
Acesso em linha:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=2;spage=277;epage=285;aulast=Li
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