Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions

The molecular architecture and assembly mechanism of intermediate filaments have been enigmatic for decades. Among those, lamin filaments are of particular interest due to their universal role in cell nucleus and numerous disease-related mutations. Filament assembly is driven by specific interaction...

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Detalhes bibliográficos
Main Authors: Giel Stalmans, Anastasia V. Lilina, Pieter-Jan Vermeire, Jan Fiala, Petr Novák, Sergei V. Strelkov
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-07-01
Colecção:Cells
Assuntos:
nuclear lamins
intermediate filaments
X-ray crystallography
chemical cross-linking
mass spectrometry
Acesso em linha:https://www.mdpi.com/2073-4409/9/7/1633
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