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A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer's disease.

Alzheimer's disease is a progressive neurodegenerative disease that manifests as memory loss, cognitive dysfunction, and dementia. Animal models of Alzheimer's disease have been instrumental in understanding the underlying pathological mechanism and in evaluation of potential therapies. Th...

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Main Authors: Aida Attar, Tingyu Liu, Wai-Ting Coco Chan, Jane Hayes, Mona Nejad, Kaichyuan Lei, Gal Bitan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3827415?pdf=render
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