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ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals
Abstract Background Immunologic aging leads to immune dysfunction, significantly reducing the quality of life of the elderly. Aged-related defects in early hematopoiesis result in reduced lymphoid cell development, functionally defective mature immune cells, and poor protective responses to vaccines...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2020-09-01
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Colecção: | Immunity & Ageing |
Assuntos: | |
Acesso em linha: | http://link.springer.com/article/10.1186/s12979-020-00198-6 |
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