Immune Cell Landscape Identification Associates Intrarenal Mononuclear Phagocytes With Onset and Remission of Lupus Nephritis in NZB/W Mice

ObjectiveA challenging issue in the clinical management of lupus nephritis (LN) is the resistance to immunosuppressive therapy. We postulated that perturbed intrarenal immune cell landscape affected LN onset and remission induction, and shedding light on the characteristics of intrarenal immune cell...

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Bibliografiske detaljer
Main Authors: Bin Li, Yanlai Tang, Xuhao Ni, Wei Chen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-11-01
Serier:Frontiers in Genetics
Fag:
lupus nephritis
immune cell landscape
mononuclear phagocytes
NZB/W mice
CIBERSORT
Online adgang:https://www.frontiersin.org/articles/10.3389/fgene.2020.577040/full
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