Safety and immunogenicity of rSh28GST antigen in humans: phase 1 randomized clinical study of a vaccine candidate against urinary schistosomiasis.

Treatment of urinary schistosomiasis by chemotherapy remains challenging due to rapid re-infection and possibly to limited susceptibility to praziquantel treatment. Therefore, therapeutic vaccines represent an attractive alternative control strategy. The objectives of this study were to assess the s...

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Main Authors: Gilles Riveau, Dominique Deplanque, Franck Remoué, Anne-Marie Schacht, Hubert Vodougnon, Monique Capron, Michel Thiry, Joseph Martial, Christian Libersa, André Capron
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3389022?pdf=render
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