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Bayesian adaptive design for pediatric clinical trials incorporating a community of prior beliefs

Abstract Background Pediatric population presents several barriers for clinical trial design and analysis, including ethical constraints on the sample size and slow accrual rate. Bayesian adaptive design methods could be considered to address these challenges in pediatric clinical trials. Methods We...

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Detalhes bibliográficos
Main Authors: Yu Wang, James Travis, Byron Gajewski
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:BMC Medical Research Methodology
Assuntos:
Acesso em linha:https://doi.org/10.1186/s12874-022-01569-x
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