Treatment with Exogenous Trypsin Expands In Vitro Cellular Tropism of the Avian Coronavirus Infectious Bronchitis Virus

The <i>Gammacoronavirus</i> infectious bronchitis virus (IBV) causes a highly contagious and economically important respiratory disease in poultry. In the laboratory, most IBV strains are restricted to replication in ex vivo organ cultures or in ovo and do not replicate in cell culture,...

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Bibliographic Details
Main Authors: Phoebe Stevenson-Leggett, Sarah Keep, Erica Bickerton
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
coronavirus
animal coronavirus
cleavage
tropism
glycoprotein
spike protein
Online Access:https://www.mdpi.com/1999-4915/12/10/1102
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