Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate.

Safe, cheap and effective adjunct therapies preventing the development of, or reducing the mortality from, severe malaria could have considerable and rapid public health impact. Oral activated charcoal (oAC) is a safe and well tolerated treatment for acute poisoning, more recently shown to have sign...

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Detalhes bibliográficos
Main Authors: J Brian de Souza, Uduak Okomo, Neal D Alexander, Naveed Aziz, Benjamin M J Owens, Harparkash Kaur, Momodou Jasseh, Sant Muangnoicharoen, Percy F Sumariwalla, David C Warhurst, Stephen A Ward, David J Conway, Luis Ulloa, Kevin J Tracey, Brian M J Foxwell, Paul M Kaye, Michael Walther
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-04-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2855344?pdf=render
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