Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

Background: Prostate cancer is the most common cancer among men in the UK. Prostate-specific antigen testing followed by biopsy leads to overdetection, overtreatment as well as undertreatment of the disease. Evidence of treatment effectiveness has lacked because of the paucity of randomised controll...

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Main Authors: Freddie C Hamdy, Jenny L Donovan, J Athene Lane, Malcolm Mason, Chris Metcalfe, Peter Holding, Julia Wade, Sian Noble, Kirsty Garfield, Grace Young, Michael Davis, Tim J Peters, Emma L Turner, Richard M Martin, Jon Oxley, Mary Robinson, John Staffurth, Eleanor Walsh, Jane Blazeby, Richard Bryant, Prasad Bollina, James Catto, Andrew Doble, Alan Doherty, David Gillatt, Vincent Gnanapragasam, Owen Hughes, Roger Kockelbergh, Howard Kynaston, Alan Paul, Edgar Paez, Philip Powell, Stephen Prescott, Derek Rosario, Edward Rowe, David Neal
Formato: Artigo
Idioma:Inglês
Publicado em: NIHR Journals Library 2020-08-01
Colecção:Health Technology Assessment
Assuntos:
prostate cancer
prostate-specific antigen testing
radical treatment
radical prostatectomy
radical radiotherapy
active monitoring
quality of life
randomised clinical trial
Acesso em linha:https://doi.org/10.3310/hta24370
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