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Study of Possible Mechanisms Involved in the Inhibitory Effects of Coumarin Derivatives on Neutrophil Activity

To specify the site of action of the synthetic coumarin derivatives 7-hydroxy-3-(4′-hydroxyphenyl) coumarin (HHC) and 7-hydroxy-3-(4′-hydroxyphenyl) dihydrocoumarin (HHDC), we evaluated their effects on extra- and intracellular reactive oxygen species (ROS) formation in phorbol-myristate-13-acetate...

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Detalhes bibliográficos
Main Authors: Katarína Drábiková, Tomáš Perečko, Radomír Nosál’, Juraj Harmatha, Jan Šmidrkal, Viera Jančinová
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2013-01-01
Colecção:Oxidative Medicine and Cellular Longevity
Acesso em linha:http://dx.doi.org/10.1155/2013/136570
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