Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment

BackgroundUnderstanding the acute kidney injury (AKI) microenvironment changes and the complex cellular interaction is essential to elucidate the mechanisms and develop new targeted therapies for AKI.MethodsWe employed unbiased single-cell RNA sequencing to systematically resolve the cellular atlas...

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Main Authors: Min Zhang, Lingling Wu, Yiyao Deng, Fei Peng, Tiantian Wang, Yinghua Zhao, Pu Chen, Jiaona Liu, Guangyan Cai, Liqiang Wang, Jie Wu, Xiangmei Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Immunology
Assuntos:
acute kidney injury
renal tubular epithelial cells
microenvironment
intercellular crosstalk
trajectory analysis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.857025/full
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