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A novel benzothiazole derivative YLT322 induces apoptosis via the mitochondrial apoptosis pathway in vitro with anti-tumor activity in solid malignancies.

Benzothiazole derivatives are known for various biological activities, and their potency in cancer therapy has received considerable attention in recent years. YLT322, a novel synthesized benzothiazole derivative, exhibits potent anti-tumor activity via inducing apoptosis both in vitro and in vivo....

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Bibliografske podrobnosti
Main Authors: Song Xuejiao, Xia Yong, Wang Ningyu, Zhang Lidan, Shi Xuanhong, Xu Youzhi, Ye Tinghong, Shi Yaojie, Zhu Yongxia, Yu Luoting
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2013-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3667852?pdf=render
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