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Toward the Synthesis and Biological Screening of a Cyclotetrapeptide from Marine Bacteria
The first synthesis of a naturally occurring tetrapeptide cyclo-(isoleucyl-prolyl-leucyl-alanyl) has been achieved using a solution-phase technique via coupling of dipeptide segments Boc-l-Pro-l-Leu-OH and l-Ala-l-Ile-OMe. Deprotection of the linear tetrapeptide unit and its subsequent cyclization g...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2010-12-01
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| Colecção: | Marine Drugs |
| Assuntos: | |
| Acesso em linha: | http://www.mdpi.com/1660-3397/9/1/71/ |
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