Engineering central pathways for industrial-level (3R)-acetoin biosynthesis in Corynebacterium glutamicum

Abstract Background Acetoin, especially the optically pure (3S)- or (3R)-enantiomer, is a high-value-added bio-based platform chemical and important potential pharmaceutical intermediate. Over the past decades, intense efforts have been devoted to the production of acetoin through green biotechnique...

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Autori principali: Lingxue Lu, Yufeng Mao, Mengyun Kou, Zhenzhen Cui, Biao Jin, Zhishuai Chang, Zhiwen Wang, Hongwu Ma, Tao Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-05-01
Serie:Microbial Cell Factories
Soggetti:
(3R)-Acetoin
Corynebacterium glutamicum
Metabolic engineering
Microbial fermentation
Citrate synthase
Green chemistry
Accesso online:http://link.springer.com/article/10.1186/s12934-020-01363-8
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