Antidiabetic effect of Chrysophyllum albidum is mediated by enzyme inhibition and enhancement of glucose uptake via 3T3-L1 adipocytes and C2C12 myotubes

Objective: To investigate the in vivo and in vitro antidiabetic potential of Chrysophyllum albidum. Methods: The effects of oral treatment with hydro-ethanolic extract (125, 250 and 500 mg/kg) of the stem bark of Chrysophyllum albidum and glibenclamide for 21 d on glucose level, serum enzyme markers...

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Hlavní autoři: Benjamin Kingsley Harley, Rita Akosua Dickson, Isaac Kingsley Amponsah, Robert A Ngala, Dorice Berkoh, Theophilus Christian Fleischer
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Medknow Publications 2020-01-01
Edice:Asian Pacific Journal of Tropical Biomedicine
Témata:
antidiabetic; c2c12 myotubes; α-glucosidase inhibition; α-amylase inhibition; glucose uptake; chrysophyllum albidum
On-line přístup:http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=9;spage=387;epage=396;aulast=Harley
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