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Niclosamide and its derivative DK‐520 inhibit RANKL‐induced osteoclastogenesis

Niclosamide is a potent inhibitor of osteoclastogenesis and bone remodeling. DK‐520 is an acyl derivative of Niclosamide and significantly increased both the plasma concentration and the duration of exposure of Niclosamide when dosed orally. However, at present the effect of DK‐520 on osteoclastogen...

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Main Authors: Yurui Jiao, Chenglong Chen, Xijian Hu, Xu Feng, Zhenqi Shi, Jie Cao, Qing Li, Yikun Zhu
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2020-08-01
Series:FEBS Open Bio
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Acceso en liña:https://doi.org/10.1002/2211-5463.12921
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