Neutralisation of peritoneal IL-17A markedly improves the prognosis of severe septic mice by decreasing neutrophil infiltration and proinflammatory cytokines.

PURPOSE: The current study aimed to elucidate the role of peritoneal fluid IL-17A in septic mice, and the effects of intraperitoneal or intravenous blockade of the IL-17A pathway by anti-IL17A antibody on survival, plasma, and peritoneal cavity cytokine profile in a murine caecal ligation and punctu...

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Detaylı Bibliyografya
Asıl Yazarlar: Jinbao Li, Yan Zhang, Jingsheng Lou, Jiali Zhu, Miaoxia He, Xiaoming Deng, Zailong Cai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2012-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC3462769?pdf=render
Etiketler: Etiketle
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