Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells.

Several factors support CLL cell survival in the microenvironment. Under different experimental conditions, IL21 can either induce apoptosis or promote CLL cell survival. To investigate mechanisms involved in the effects of IL21, we studied the ability of IL21 to modulate gene and miRNA expressions...

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Detalhes bibliográficos
Main Authors: Loris De Cecco, Matteo Capaia, Simona Zupo, Giovanna Cutrona, Serena Matis, Antonella Brizzolara, Anna Maria Orengo, Michela Croce, Edoardo Marchesi, Manlio Ferrarini, Silvana Canevari, Silvano Ferrini
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4549109?pdf=render
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