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Prion protein expression and processing in human mononuclear cells: the impact of the codon 129 prion gene polymorphism.

BACKGROUND:So far, all clinical cases of new variant Creutzfeldt-Jakob disease (vCJD), thought to result from the Bovine Spongiform Encephalopathy (BSE) prion agent, have shown Methionine-Methionine (M/M) homozygosity at the M129V polymorphism of the PRNP gene. Although established, this relationshi...

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Main Authors: Christiane Segarra, Sylvain Lehmann, Joliette Coste
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2009-06-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC2686158?pdf=render
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