Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks

BANK1 is a susceptibility gene for several systemic autoimmune diseases in several populations. Using the genome-wide association study (GWAS) data from Europeans (EUR) and African Americans (AA), we performed an extensive fine mapping of ankyrin repeats 1 (BANK1). To increase the SNP density, we us...

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Main Authors: Manuel Martínez-Bueno, Nina Oparina, Mikhail G. Dozmorov, Miranda C. Marion, Mary E. Comeau, Gary Gilkeson, Diane Kamen, Michael Weisman, Jane Salmon, Joseph W. McCune, John B. Harley, Robert Kimberly, Judith A. James, Joan Merrill, Courtney Montgomery, Carl D. Langefeld, Marta E. Alarcón-Riquelme
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Assuntos:
autoimmune disorders
systemic lupus erythematosus
genetics
BANK1
transethnic genetic studies
Acceso en liña:http://www.mdpi.com/1422-0067/19/8/2331
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