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Global Population Structure of the Genes Encoding the Malaria Vaccine Candidate, Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1).

BACKGROUND: The Plasmodium vivax Apical Membrane Antigen 1 (PvAMA1) is a promising malaria vaccine candidate, however it remains unclear which regions are naturally targeted by host immunity and whether its high genetic diversity will preclude coverage by a monovalent vaccine. To assess its feasibil...

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Autors principals: Alicia Arnott, Ivo Mueller, Paul A Ramsland, Peter M Siba, John C Reeder, Alyssa E Barry
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS Neglected Tropical Diseases
Accés en línia:http://europepmc.org/articles/PMC3814406?pdf=render
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