FH535 inhibited migration and growth of breast cancer cells.

There is substantial evidence indicating that the WNT signaling pathway is activated in various cancer cell types including breast cancer. Previous studies reported that FH535, a small molecule inhibitor of the WNT signaling pathway, decreased growth of cancer cells but not normal fibroblasts, sugge...

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Autors principals: Joji Iida, Jesse Dorchak, John R Lehman, Rebecca Clancy, Chunqing Luo, Yaqin Chen, Stella Somiari, Rachel E Ellsworth, Hai Hu, Richard J Mural, Craig D Shriver
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3439405?pdf=render
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