Epiregulin, epigen and betacellulin antibodies and axial elongation in young guinea pigs with lens-induced myopization

Abstract Background To examine an effect of intravitreally applied antibodies against epidermal growth factor family members, namely epiregulin, epigen and betacellulin, on ocular axial elongation. Methods The experimental study included 30 guinea pigs (age:3–4 weeks) which underwent bilateral lens-...

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Hauptverfasser: Li Dong, Rui-Heng Zhang, Wen-Da Zhou, Yi-Fan Li, He-Yan Li, Hao-Tian Wu, Xu-Han Shi, Jost. B. Jonas, Wen-Bin Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-04-01
Schriftenreihe:BMC Ophthalmology
Schlagworte:
Myopia
Epidermal Growth Factor
Axial Length
Epiregulin
Epigen
Betacellulin
Online Zugang:https://doi.org/10.1186/s12886-022-02417-8
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