Nanoparticles in 472 Human Cerebrospinal Fluid: Changes in Extracellular Vesicle Concentration and miR-21 Expression as a Biomarker for Leptomeningeal Metastasis

Leptomeningeal metastasis (LM) has a poor prognosis and is difficult to diagnose and predict the response of treatment. In this study, we suggested that the monitoring of changes in the concentration of extracellular vesicles in cerebrospinal fluid could help diagnose or predict outcomes for LM. We...

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Main Authors: Kyue-Yim Lee, Ji Hye Im, Weiwei Lin, Ho-Shin Gwak, Jong Heon Kim, Byong Chul Yoo, Tae Hoon Kim, Jong Bae Park, Hyeon Jin Park, Ho-Jin Kim, Ji-Woong Kwon, Sang Hoon Shin, Heon Yoo, Changjin Lee
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-09-01
Series:Cancers
Assuntos:
biomarker
cerebrospinal fluid
extracellular vesicle
microRNA
leptomeningeal metastasis
Acceso en liña:https://www.mdpi.com/2072-6694/12/10/2745
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