Detection and Its Clinical Significance of EGFR Gene Mutation and Gene Amplification in 187 Patients with Non-small Cell Lung Cancer

Background and objective It has been demonstrated that epidermal growth factor receptor (EGFR) signal pathway had an important role in the oncogenesis and development of non-small cell lung cancer (NSCLC). Small-molecule tyrosine kinase inhibitors (TKIs) that target at the kinase domain of EGFR are...

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Main Authors: Qinghua ZHOU, Jun CHEN, Zuoqing SONG, Weiqiang WAN, Xiaoming QIU, Daxing ZHU, Sen WEI, Yuli WANG, Yongwen LI, Jing WANG, Gang CHEN, Ying LI, Hongyu LIU
Formato: Artigo
Idioma:Chinês
Publicado em: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2009-12-01
Colecção:Chinese Journal of Lung Cancer
Assuntos:
Lung neoplasms
Epidermal growth factor receptor
Gene mutation
Gene amplification
Acesso em linha:http://www.lungca.org/index.php?journal=01&page=article&op=viewFile&path[]=10.3779%2Fj.issn.1009-3419.2009.12.01&path[]=1225
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