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Thrombin induces morphological and inflammatory astrocytic responses via activation of PAR1 receptor
Abstract Spinal cord injury (SCI) will result in the significant elevation of thrombin production at lesion site via either breakage of blood-spinal cord barrier or upregulated expression within nerve cells. Thrombin-induced activation of the protease activated receptors (PARs) evokes various pathol...
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Hauptverfasser: | , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Nature Publishing Group
2022-04-01
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Schriftenreihe: | Cell Death Discovery |
Online Zugang: | https://doi.org/10.1038/s41420-022-00997-4 |
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