Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes

Abstract Background The Wnt/β-catenin signaling pathway plays an important role in the development of second heart field (SHF Isl1+) that gives rise to the anterior heart field (AHF) cardiac progenitor cells (CPCs) for the formation of the right ventricle, outflow tract (OFT), and a portion of the i...

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Detalhes bibliográficos
Main Authors: Yong Fan, Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Nicole Min Qian Pek, Jin Hui Hor, Shi-Yan Ng, Boon-Seng Soh
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-12-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Wnt signaling
Matured cardiomyocytes
Cardioproliferation
N-cadherin
GSK inhibitor
Embryonic stem cells
Acesso em linha:http://link.springer.com/article/10.1186/s13287-018-1086-8
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