Resting-State Connectivity of the Left Frontal Cortex to the Default Mode and Dorsal Attention Network Supports Reserve in Mild Cognitive Impairment

Reserve refers to the phenomenon of relatively preserved cognition in disproportion to the extent of neuropathology, e.g., in Alzheimer’s disease. A putative functional neural substrate underlying reserve is global functional connectivity of the left lateral frontal cortex (LFC, Brodmann Area 6/44)....

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Main Authors: Nicolai Franzmeier, Jens Göttler, Timo Grimmer, Alexander Drzezga, Miguel A. Áraque-Caballero, Lee Simon-Vermot, Alexander N. W. Taylor, Katharina Bürger, Cihan Catak, Daniel Janowitz, Claudia Müller, Marco Duering, Christian Sorg, Michael Ewers
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-08-01
Colecção:Frontiers in Aging Neuroscience
Assuntos:
cognitive reserve
mild cognitive impairment
frontoparietal control network
memory
functional connectivity
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00264/full
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