Evaluation of Toxicity and Neural Uptake In Vitro and In Vivo of Superparamagnetic Iron Oxide Nanoparticles

Superparamagnetic iron oxide nanoparticles (SPIO-NPs) have great potential to be used in different pharmaceutical applications, due to their unique and versatile physical and chemical properties. The aim of this study was to quantify in vitro cytotoxicity of dextran 70,000-coated SPIO-NPs labelled/u...

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Hauptverfasser: Muhammad Kamran Khalid, Muhammad Asad, Petra Henrich-Noack, Maxim Sokolov, Werner Hintz, Lisa Grigartzik, Enqi Zhang, Alexander Dityatev, Berend van Wachem, Bernhard A. Sabel
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2018-09-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
superparamagnetic iron oxide nanoparticles (SPIO-NPs)
drug delivery
in vitro toxicity
cellular uptake
Online Zugang:http://www.mdpi.com/1422-0067/19/9/2613
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