Diagnostic accuracy of plasma kynurenine/tryptophan ratio, measured by enzyme-linked immunosorbent assay, for pulmonary tuberculosis

Introduction: The World Health Organization has identified the need for a non-sputum-based test capable of detecting active tuberculosis (TB) as a priority. The plasma kynurenine-to-tryptophan (K/T) ratio, largely mediated by activity of the enzyme indoleamine 2,3-dioxygenase, may have potential as...

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Main Authors: Clement Gascua Adu-Gyamfi, Tracy Snyman, Lillian Makhathini, Kennedy Otwombe, Fatoumatta Darboe, Adam Penn-Nicholson, Michelle Fisher, Dana Savulescu, Christopher Hoffmann, Richard Chaisson, Neil Martinson, Thomas Jens Scriba, Jaya Anna George, Melinda Shelley Suchard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-10-01
Colecção:International Journal of Infectious Diseases
Assuntos:
IDO
Kynurenine/tryptophan ratio
Sensitivity
Specificity
TB
HIV
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1201971220306573
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