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NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses

Uncontrolled fibrosis in organs like heart, kidney, liver and lung is detrimental and may lead to end-stage organ failure. Currently there is no effective treatment for fibrotic disorders. Transforming growth factor (TGF)-β has a fundamental role in orchestrating the process of fibrogenesis; however...

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Hlavní autoři: Fan Jiang, Guei-Sheung Liu, Gregory J. Dusting, Elsa C. Chan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014-01-01
Edice:Redox Biology
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2213231714000275
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